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The new crown epidemic that occurred at the end of 2019 made more people know about hypochlorous acid disinfectant, but hypochlorous acid has more functions in addition to its disinfection and sterilization performance. Today we will explain it in detail for you.
Sterilization is the main function of hypochlorous acid. The surface of the cell membrane of microorganisms is negatively charged, so hypochlorite (ClO-, which is also negatively charged) cannot easily enter the interior of the cell, while hypochlorous acid (HClO) is neutral. Small molecules that can penetrate the cell membrane, enter the interior of the cell, and react with the DNA and mitochondria inside it, causing it to die. This function does not need to be repeated, and many other functions of hypochlorous acid are also derived on this basis.
Electrolyzed hypochlorous acid water is an immersion type antiseptic and fresh-keeping agent, which can achieve the purpose of anti-corrosion and fresh-keeping by soaking and spraying. Respiratory metabolism.
Studies have shown that slightly acidic hypochlorous acid water not only has a fresh-keeping effect on fruits and vegetables, but also has a good fresh-keeping effect on livestock and poultry products and aquatic products, and can also ensure stable quality indicators.
Hypochlorous acid water has excellent removal effect on dimethyl disulfide (smell like rotten cabbage), ammonia gas (smell like urine), propionic acid (irritating odor with sweet and sour and burnt taste), while the sulfur Hydrogen (smell like rotten eggs), trimethylamine (smell like stinky fish), n-butyric acid (smell of sweat), n-valeric acid (smell of wet socks) also performed well. For details, please go to the official account to find previous articles: new applications | things you don't know about electrolyzed water deodorization...
Hypochlorous acid water can also be used for indoor formaldehyde removal. Due to its strong oxidizing property, hypochlorous acid water has a certain removal effect on formaldehyde in the air by spraying, and its reaction is as follows:
HCHO+HClO=HCOOH+HCl
The data shows that when the hypochlorous acid water is used for atomization for 10min, the formaldehyde concentration in the 0.8m³ incubator drops from 0.95ppm to 0.21ppm, and the decline rate reaches 77.9%. When the formaldehyde concentration is near the standard critical value, the formaldehyde concentration decreases slowly with the extension of time, and it takes about 6 minutes to drop from 0.11ppm to 0.07ppm.
Wound healing is a physiological process in which a variety of cytokines and growth factors participate in a coordinated interaction, involving cell biology such as cell movement, adhesion, proliferation and differentiation.
Stabilized HOCl solution acts as an ideal wound care solution with powerful and rapid killing effects on different types of microorganisms, biofilms and bacteria in biofilms. Second, it has a dose-dependent beneficial effect on fibroblast and keratinocyte migration. At the same time, studies have shown that 0.01% hypochlorous acid solution can increase the number of new capillaries in rat wound granulation tissue and increase the level of fibroblasts in rat wound granulation tissue, which can provide a basis for clinical use. These characteristics make HOCl solutions ideal wound care agents.
A study by T. Fukuyama of North Carolina State University found that treatment with HOCl hydrogel prevented the development of skin lesions and scratching. When administered after the lesions had fully developed, HOCl reduced skin lesions and scratching behavior to a similar extent to the positive control 0.1% betamethasone dipropionate ointment. The therapeutic effect of HOCl was demonstrated by reducing the secretion of inflammatory cytokines in the affected skin tissue of NC/Nga mice. Furthermore, HOCl significantly reduced IL-12 production in mBMDCs. Following the study, several pruritic agents resected from dorsal root ganglion neurons of NC/Nga mice had impaired responses, confirming the attenuation of scratching behavior. These data suggest that HOCl directly reduces sensory responses, thereby significantly reducing itching and inflammation in vivo.
Slightly acidic hypochlorous acid water replaces or partially replaces chemical pesticides for crop disease control, which not only reduces the use of chemical pesticides, but also has huge advantages in terms of safety, convenience and economy.
The research group of Professor Li Lite from China Agricultural University took the lead in carrying out the research on the prevention and control of crop diseases with electrolyzed water in my country. From 2003 to 2009, the research group of the research group showed that the acid electrolyzed hypochlorous acid water was effective against grape anthracnose, cucumber powdery mildew, wheat Diseases such as stripe rust and tomato leaf mold have good control effects.
In 2003, the Japanese Ministry of Agriculture, Forestry and Fisheries identified hypochlorous acid water (limited to those obtained by electrolysis of hydrochloric acid or potassium chloride aqueous solution) as a specific pesticide.
The use of electrolyzed hypochlorous acid water to irrigate plants also showed an obvious effect of promoting growth. This effect is due to the inhibition of soil-borne diseases on the one hand, and the activation of many mineral elements in the soil on the other hand. , thereby promoting the growth, development and metabolism of plants; the treated water has smaller molecular groups, which is more conducive to the progress of water metabolism and achieves the purpose of promoting growth. Its growth-promoting effect is multi-faceted. However, the growth-promoting effect of hypochlorous acid water on plants is not yet clear, and there may be differences between different crops, which needs to be further studied.
Aflatoxin is produced by Aspergillus flavus and Aspergillus parasiticus. Among the aflatoxins, aflatoxin B1 (AFB1) is the most toxic and carcinogenic.
AFB1 has a wide distribution range. AFB1 contamination has been detected in grain and oil foods, animal and plant foods, such as peanuts, corn, rice, wheat, beans, nuts, meat, milk and dairy products, and aquatic products. Among them, peanuts and corn are the most polluted. All countries attach great importance to the problems of Aspergillus flavus infection and toxin B1 contamination in agricultural products, food and feed. In 1993, AFB1 was classified as a class 1 carcinogen by the World Health Organization's Cancer Research Agency, and it is the most toxic natural poison known so far.
Yu uses acidic electrolyzed hypochlorous acid water to remove AFB1, and identifies and evaluates the resulting products. To reveal the mechanism of AFB1 scavenging by acid electrolysis of hypochlorous acid water. The test results show that the relative molecular mass of the main product generated by acid electrolysis of hypochlorous acid water to remove AFB1 is 364, and the chemical formula is C17H13ClO7. Combined with NMR analysis, the unknown product was confirmed to be 8-chloro-9-hydroxy-Aflatoxin B1 (8-Cl-9-OH-AFB1). It is an organic molecule with amphiphilic properties. The safety research results of the product show that the product has no mutagenicity, its median lethal dose concentration IC50 value is about 150 mmol/L, and it has no toxic effect on cells. The application safety of acid electrolytic hypochlorous acid water to remove AFB1 was clarified, which provided a safe, effective and promising new way to remove AFB1 pollution.
Mites are microscopic pests that are not easily visible to the naked eye, and there are many types. So far, more than 40 species of mites have been found living in the living room, among which there are more than ten species related to human health. The most common are dust mites, powder mites, worms, scabies mites and so on. The survey shows that about 97% of adults are infected with mites, of which dust mites are the main ones. Dust mite carcasses, secretions, and excreta are allergens that can cause disease. They are distributed in carpets, sofas, plush toys, quilts, cushions, mattresses and pillow cores, etc., and feed on human sweat, secretions, and shed skin flakes, and reproduce very quickly.
Laboratory studies have shown that hypochlorous acid is effective in killing Demodex nymphs, as well as Bacillus oleifera and Staphylococcus aureus that live on the eyelids and in the Demodex gut. In addition, HOCl neutralizes inflammatory toxins released by mites and bacteria.
