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The new crown epidemic that occurred at the end of 2019 made people realize the importance of disinfection. Among them, hypochlorous acid disinfectant has received great attention due to its safety, high efficiency, broad-spectrum sterilization, and wide application range.
However, hypochlorous acid is a new type of disinfectant, and the public's awareness of it is relatively low, and the concepts of acidic oxidizing potential water, slightly acidic electrolyzed water, slightly acidic hypochlorous acid water, etc. are the same as hypochlorous acid disinfectants. Relevance, there are differences.
The main components of electrolyzed acidic water, slightly acidic electrolyzed water, and slightly acidic hypochlorous water are hypochlorous acid. In order to let the public have a better understanding of this knowledge, we will take hypochlorous acid as the starting point and make detailed descriptions. introduce.
The chemical formula of hypochlorous acid is HClO and the structural formula is HO-Cl. The valence of chlorine is +1, which is the lowest oxyacid of chlorine, but its oxidizing property is extremely strong among oxyacids of chlorine. It is chlorine. The second most oxidizing acid among oxyacids.
Hypochlorous acid plays an important role in the human immune system. In the human body, hypochlorous acid is produced by the myeloperoxidase-H2O2-Cl- system in neutrophils. When microorganisms invade, neutrophils, as the first line of defense of the human immune system, are activated to initiate the expression of related inflammatory genes and a series of intracellular events occur.
First of all, activated neutrophils will play a phagocytosis to phagocytose microorganisms to form phagosomes. There are a large number of particles in neutrophils. These particles contain myeloperoxidase. After the formation of phagosomes, the neutrophils will undergo a degranulation process. The membrane of cytoplasmic particles will fuse with the phagosomes to convert myeloperoxidase. The enzyme is excreted into the phagosome to form a phagolysosome. At the same time, the NADPH oxidase existing on the plasma membrane of neutrophils is activated, neutrophils undergo respiratory bursts, consume a large amount of oxygen to produce superoxide anions (O2-), and O2-further undergoes disproportionation to form H2O2. Myeloperoxidase catalyzes H2O2, Cl- to form hypochlorous acid:
H2O2 + 2Cl－→2HClO
Studies have shown that 106 activated neutrophils can produce about 2 × 10-7 mol hypochlorous acid within a 2 h incubation time. Neutrophils generate sufficient hypochlorous acid through the above myeloperoxidase-H2O2-Cl- system, which plays an important role in killing microorganisms.
Definition of chlorine-containing disinfectant: Chlorine-containing disinfectant refers to a disinfectant that dissolves in water to produce hypochlorous acid with microbicidal activity.
The well-known 84 disinfectant (sodium hypochlorite) and bleaching powder (calcium hypochlorite) in our daily life are all inorganic chlorine-containing disinfectants, but the performance of inorganic chlorides is unstable, so people invented organic chlorine-containing disinfectants (such as dichloroisochlorite). Sodium cyanurate, trichloroisocyanuric acid, ammonium chloride T, etc.).
Whether it is an inorganic chlorine-containing disinfectant or an organic chlorine-containing disinfectant, the final active ingredient after it is dissolved in water is hypochlorous acid.
Hypochlorous acid disinfectant is suitable for the disinfection of general object surfaces, medical equipment, medical waste, food and drink utensils, fabrics, fruits and vegetables and water in medical and health institutions, public health places, and households. It can also be used for air and secondary water supply equipment. Disinfection of facility surfaces, hands, skin and mucous membranes.
